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. 2018 Jan 29;41(2):119–126. doi: 10.14348/molcells.2018.2235

Fig. 3. miR-612 inhibits melanoma cell migration and invasion.

Fig. 3

(A) In vitro wound healing assays demonstrated that miR-612 overexpression significantly inhibited the migration of SK-MEL-28 and A375 cells. (B) Transwell invasion assay. Ectopic expression of miR-612 significantly suppressed the invasion of SK-MEL-28 and A375 cells. Top, representative images of invaded cells. Bottom, quantification of cell invasion. *P < 0.05 relative to vector-transfected cells. (C) Western blot analysis of E-cadherin (E-cad) and vimentin (Vim) protein levels in SK-MEL-28 and A375 cells transfected with indicated constructs. Numbers indicate normalized protein levels, which were determined from three independent experiments.