Fig. 2. Expression of Redrum in hematopoietic tissues.

Whole mount RNA in situ hybridization show expression of Redrum in developing liver (arrowhead in A). Transverse sections from embryos with indicated days show expression in the liver (A). Note the peak of expression in E12.5 (A) which was also the case in the RT-PCR analysis (B) carried out with liver tissues isolated from indicated stages. In adult mice, liver was negative for Redrum (B) while bone marrow was positive during both pregnant and non-pregnant states (C). Strong expression in the spleen was seen only during pregnancy (C). (BM, bone marrow; P, pregnant; N, non-pregnant)