TABLE 2.
Amplification microarray M. tuberculosis and resistance-associated gene detection rate
| Sampleb | Target | Detection rate (%) |
|||
|---|---|---|---|---|---|
| Smear-positive specimens |
Smear-negative specimens |
||||
| Culture-positive specimens (n = 107 or 108a) | Culture-negative specimens (n = 8) | Culture-positive specimens (n = 5) | Culture-negative specimens (n = 9) | ||
| Sputum extracts | M. tuberculosis | 100 | 100 | 80 | 89 |
| rpoB | 100 | 100 | 100 | 100 | |
| katG | 100 | 88 | 100 | 100 | |
| inhA | 100 | 100 | 100 | 100 | |
| Sediment extracts | M. tuberculosis | 100 | 100 | 100 | 67 |
| rpoB | 99 | 100 | 100 | 83 | |
| katG | 100 | 100 | 100 | 80 | |
| inhA | 100 | 100 | 80 | 100 | |
a
There were 107 and 108 smear- and culture-positive sputum and sediment extracts, respectively.
b
Resistance-associated genes were scored only if M. tuberculosis (the IS6110 element) was detected by the amplification microarray.