TABLE 1.

Overview of Xpert-positive, culture-negative (false-positive) patients with a history of previous TB^a

Patient no.	HIV infection status	Morbidity score at recruitmentb	No. of WHO TB symptoms (symptom type) at recruitmentc	WHO symptom criteria for active TB investigation metd	Chest radiography findings	Sputum Xpert and culture results prior to bronchoscopy	Time (mo) from enrollment to repeat sputum testing	BALF Xpert and culture results
RX059	P	0	1 (current cough)	Yes	Compatible with active TB, right unilateral cavitation	Xpert negative, culture negative	2	Bronchoscopy declined
RX061	N	0	1 (cough for ≥2 wk)	Yes	Compatible with old TB	Xpert negative, culture negative	2	Xpert negative, culture negative
RX065	P	0	0	No	Compatible with active TB, no cavitation	Xpert negative, culture negative	2	Xpert negative, culture negative
RX076	P	0	0	No	Compatible with active TB, no cavitation	Xpert positive, culture negative	2	Xpert positive, culture negative
RX099	P	2	3 (cough for ≥2 wk, wt loss, fatigue)	Yes	Compatible with active TB, bilateral cavitation	Xpert negative, culture negative	2	Xpert positive, culture negative
RX101	P	0	0	No	Compatible with active TB, no cavitation	Xpert positive, culture negative	2	Xpert negative, culture negative
RX102	P	1	0	No	Compatible with active TB, no cavitation	Xpert negative, culture negative	2	Bronchoscopy not done
RX108	N	0	1 (current cough)	No	Compatible with active TB, no cavitation	Xpert positive, culture negative	2	Xpert positive, culture negative
RX115	P	0	0	No	Compatible with active TB, left unilateral cavitation	Xpert negative, culture negative	2	Xpert positive, culture negative
RX122	P	2	3 (wt loss, fever, chest pain)	Yes	Compatible with old TB	Xpert negative, culture negative	2	Bronchoscopy declined
RX124	P	1	1 (cough for ≥2 wk)	Yes	Compatible with old TB	Xpert positive, culture negative	1	Xpert positive, culture negative
RX146	P	0	0	No	Compatible with active TB, no cavitation	Declined further participation after first visit	NA	Bronchoscopy declined
RX502	P	0	0	No	Not done	Xpert positive, culture negative	3	Xpert negative, culture negative
RX512	P	7	6 (cough for ≥2 wk, wt loss, fever, night sweats, fatigue, chest pain)	Yes	Compatible with active TB, no cavitation	Xpert positive, culture negative	1	Xpert negative, culture negative
RX539	P	1	0	No	Compatible with active TB, right unilateral cavitation	Xpert negative, culture negative	2	Xpert negative, culture negative
RX565	N	0	0	No	Compatible with active TB, cavitation present but extent unrecorded	Xpert negative, culture negative	1	Xpert positive, culture negative

^aAll patients were clinically well without treatment after long-term follow-up. Abbreviations: BALF, bronchoalveolar lavage fluid; P, positive; N, negative; TB, tuberculosis; WHO, World Health Organization; NA, not applicable.

^bThe morbidity score refers to the TBscore, which has been described previously (21).

^cSee reference 32.

^dSee references 32 and 33.