FIG 3.

Binding of recombinant E80 antigen to sera from patients with remote (A) and recent (B) ZIKV and/or DENV infection. Sera from primary (filled symbols) and secondary (unfilled symbols) ZIKV- and DENV-infected patients were diluted 1:20, and the IgG antibodies bound to recombinant E80 antigen were measured by ELISA. Sera collected ≥12 weeks after infection were defined as remote infections, and sera collected within the first 12 weeks were considered to represent recent infections. The horizontal lines represent the means.