Table 1. Characteristics of included studies.
| First author (year) | Country | Design | No. of paients | No. of eyes | Mean age±SD (y) |
M/F (n) |
Intervention regimen | Follow up (mo) | ||
| Glaucoma surgery | Combined surgery | Glaucoma surgery | Combined surgery | |||||||
| Bilgin (2014) | Turkey | CCT | 49 | 52 | 69.6±7.1 | 66.6±9.5 | 15/11 | 12/11 | NPDS vs phaco-NPDS | 30.9/28.7 |
| Bull (2011) | Germany | RCT | 101 | 101 | 67.3±9.9 | 67.3±9.9 | - | - | Canaloplasty vs phacocanaloplasty | 36/36 |
| Cillino (2004) | Italy | RCT | 65 | 65 | 68.6±1.7 | 71.7±2.0 | 9/8 | 8/7 | NPDS vs phaco-NPDS | 24/24 |
| 71.3±1.2 | 74.6±1.1 | 8/10 | 9/6 | PT vs phaco-PT | 24/24 | |||||
| D'Eliseo (2003) | Italy | RCT | 42 | 42 | 71.5 | 79 | 15/6 | 8/13 | DS vs Phaco-DS | 12/12 |
| Ting (2012) | USA | Pro | 713 | 713 | 68±15 | 74±9 | 181/256 | 104/155 | Trabeculectomy vs cataract extraction and trabeculectomy | 12/12 |
| Wishart (2003) | England | Pro | 151 | 192 | 66.9±10.1 | 78.9±12.3 | 13/7 | 23/33 | VC vs phaco-VC | 36.4/32.2 |
| 67±11.7 | 77±8.9 | 21/22 | 17/18 | DS vs phaco-DS | 36.3/35.1 | |||||
| Wishart (2002) | UK | Pro | 73 | 101 | 75.2 | 75.2 | - | - | VC vs phaco-VC | 36/36 |
| Parikh (2016) | USA | Retro | 753 | 753 | 69±11 | 72±9 | - | - | Trabeculectomy vs phaco-trabeculectomy | 12/12 |
| Tetz (2015) | Germany | Retro | 112 | 112 | 63.5±9.9 | 74.8±9.0 | 44/38 | 12/18 | Canaloplasty vs phacocanaloplasty | 36/36 |
| Sałaga-Pylak (2013) | Poland | Retro | 122 | 122 | 70.8±6.3 | 70.7±7.0 | 32/40 | 12/38 | TrabMMC vs phaco-trabMMC | 18/18 |
| Chihara (2011) | Japan | Retro | 789 | 789 | 60.2±17.6 | 68.7±13.9 | - | - | TrabMMC vs phaco-trabMMC | 6/6 |
| 60.2±17.6 | 71.4±9.6 | VC vs phaco-VC | ||||||||
| Rotchford (2007) | UK | Retro | 63 | 63 | 72.8±7.6 | 79.2±7.5 | 17/13 | 16/16 | MT vs phaco-MT | 43.5/41.8 |
| Marek (2006) | Poland | Retro | 35 | 67 | - | - | - | - | DS vs phaco-DS | 12/12 |
| Uretmen (2003) | Turkey | Retro | 40 | 40 | 71.8±7.7 | 71.1±6.4 | 10/10 | 12/8 | VC vs phaco-VC | 12/12 |
CCT: Clinical controlled trial; RCT: Prospective randomized controlled trial; Pro: Prospective non-randomized; Retro: Retrospective; NPDS: Non-penetrating deep sclerectomy; Phaco: Phacoemulsification; DS: Deep sclerectomy; VC: Viscocanalostomy; MT: Microtrabeculectomy; PMT: Phaco-microtrabeculectomy; TrabMMC: Trabeculectomy with mitomycin C; PT: Punch trabeculectomy.