Table 5. Quantitative Evaluation of Staging Systems Stratified by Data Set.
| Category of Evaluation | Siteman Registry Data | NCDB Data | ||||
|---|---|---|---|---|---|---|
| AJCC | FSSS | CSSS | AJCC | FSSS | CSSS | |
| Monotonicity of survival gradient | Yes | Yes | Yes | Yes | Yes | Yes |
| Overall survival gradient, % | 16 | 33 | 37 | 21 | 39 | 49 |
| Variance reduction score | 0.05 | 0.13 | 0.21 | 0.08 | 0.15 | 0.11 |
| Log rank for linear trend | 28.38 | 142.77 | 151.77 | 4268.83 | 14 375.62 | 11 457.96 |
| C statistic (95% CI) | 0.63 (0.56-0.71) | 0.80 (0.75-0.85) | 0.74 (0.67-0.81) | 0.66 (0.65-0.66) | 0.71 (0.70-0.72) | 0.62 (0.61-0.62) |
Abbreviations: AJCC, The American Joint Committee on Cancer; CSSS, clinical severity staging system; FSSS, functional severity staging system; NCDB, National Cancer Database.