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Duvelisib changes TAM polarization in vivo. (A) Schematic of the in vivo experiment for macrophage polarization in the presence of an AITL PDX. (B) Spleen sizes and spleen weights of mice engrafted with DFTL-78024 and treated with vehicle or duvelisib. Quantification of total macrophages by F4/80 and CD11b staining (C) and macrophage polarization by CD206 and MHC-II staining (D) in vehicle- or duvelisib-treated animals. Statistics: unpaired Student t test.
