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. 2017 Dec 20;22(3):1517–1526. doi: 10.1111/jcmm.13419

Figure 2.

Figure 2

Gallic acid attenuates left ventricular hypertrophy in spontaneously hypertensive rats (A) WGA (top panel) and H&E (bottom panel) staining performed to evaluate the increased size in myocytes. Scale bar = 50 μm. (B) Cross‐sectional area of the left ventricle was evaluated (= 8 per group). ***< 0.001 compared with WKY rats. ### < 0.001 versus SHRs. (C) The ratio of the left ventricular weight to tibia length (mg/mm) in WKY, SHR, SHR+GA (= 8 per group). ***< 0.001 compared with WKY rats. ### < 0.001 versus SHRs. (D, E) The mRNA levels of ANP and BNP were evaluated by real‐time RT‐PCR from three groups (= 14). The transcript levels were normalized to those for 18S and presented as relative values. ***< 0.001 versus WKY rats. # < 0.05 versus SHRs.