Table 1.

Patient and tumour features in studies on endoscopic/microscopic approach for non‐functioning pituitary adenomas

	Number of endoscopic/microscopic studies	Number of endoscopic/microscopic patients	Endoscopic pooled proportion (95%CI)	I 2% (P value for heterogeneity)	Microscopic pooled proportion (95%CI)	I 2% (P value for heterogeneity)	P value for difference
Patient characteristics
Age	11/5	1381/389	57.73 (51.35–56.10)	0 (0.972)	56.22 (54.07–58.37)	0 (0.971)	0.580
Males%	19/5	3458/389	57 (54–60)	62.8 (<0.001)	63 (58–68)	17.1 (0.305)	0.024
Presenting symptoms
Hypopituitarism%	8/3	892/269	48 (28–68)	97.9 (<0.001)	23 (9–37)	86.5 (0.001)	<0.001
Pre‐operative visual deficit%	13/2	2200/226	57 (49–65)	92.7 (<0.001)	67.4 (0.080)	44 (33–56)	<0.001
Tumour characteristics
Macroadenoma%	7/2	1030/167	86 (76–95)	77.5 (0.012)	63 (53–73)	0 (<0.001)	<0.001
Superasellae invasion%	4/1	967/144	53 (6–100)	99.5 (<0.001)	11	NA	<0.001
Intrasellae/Clinvus invasion%	3/1	476/144	55 (−20–131)	99.5 (<0.001)	12	NA	<0.001
Knosp score 0–2%	10/4	2216/354	45 (36–55)	94.9 (<0.001)	45 (29–60)	89.4 (<0.001)	0.979
Knosp score 3–4%	10/4	2216/354	55 (45–64)	94.9 (<0.001)	55 (40–71)	89.4 (<0.001)	0.979
Maximum tumour diameter (mm)	9/2	1576/226	27.15 (16.35–37.95)	0 (0.971)	27.65 (10.50–44.80)	0 (0.868)	0.548