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. 2017 Dec 20;22(3):1614–1626. doi: 10.1111/jcmm.13436

Figure 1.

Figure 1

Effect on cell vitality of a combination of ATO and Dasatinib on Ph+ ALL cell lines. (A) Concentration‐dependent and time course‐dependent effects of ATO or Dasatinib on SUP‐B15 and TOM‐1 cells. Cells were treated with the indicated concentrations of ATO or Dasatinib for the indicated time courses. Cell viability was measured by CCK‐8. (B) Synergistic effects of ATO and Dasatinib on SUP‐B15 and TOM‐1 cells. Cell viability was analysed after a treatment with ATO and/or Dasatinib at the indicated concentrations. Each bar represents the mean ± S.E.M, n = 3. *P < 0.05; **P < 0.01; ***P < 0.001 versus ATO, Dasatinib and control group. A, ATO; D, Dasatinib.