Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 15;22(3):1944–1956. doi: 10.1111/jcmm.13480

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

A putative summarized presentation of our data on a possible role of Zn²⁺ transporters on an intersection‐pathway associated with increased cytosolic free Zn²⁺ and PKCα‐activation and induction of heart failure via development of ER stress. The thickness of the arrows related with the transporters show the alterations in their expression levels. Here, thick red arrows represent increased level of pPKC as phosphorylated PKCα and increased [Zn²⁺]_i, intracellular‐free Zn²⁺ concentration in cells under heart failure. The thickness of red arrows related with localization of Zn²⁺ transporters represent increase/decrease expression levels. S(E)R represents sarco(endo)plasmic reticulum.