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Down‐regulation of Myoferlin disrupted VM structures formation in vitro. A, Myoferlin was knockdown by siRNA with three different sequences. B, Cell proliferation was slightly affected after knockdown of Myoferlin. C, Down‐regulating Myoferlin inhibited VM structures formation on Matrigel by A375 cells (100×). Each condition was carried out with three individual replicates. *P < 0.05; **P < 0.01.
