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. 2018 Feb 23;17:91. doi: 10.1186/s12936-018-2232-6

Table 1.

Correlation between parasitaemia and sample applicability for direct WGS

Parasitaemia Applicable count Applicable % Inapplicable count Inapplicable %
< 10,000 28 58 20 42
10,000 48 72 19 28
20,000 5 100 0 0
30,000 20 74 7 26
40,000 24 77 7 23
> 50,000 19 90 2 10

OR = 1.29 (95% CI 1.07–1.58) p = 0.009

Correlation between parasitaemia and sample applicability for direct WGS N = 199, parasitaemias are given as parasites/µl, calculated according to a leukocyte count of 8000 per µl whole blood. Parasites and leukocytes were counted by microscopy, counting until 500 parasites or 200 leukocytes. Samples were grouped in five groups according to parasitaemia, corresponding to intervals of 10,000 parasites/µl. The minimum parasitaemia recorded in group 1 was 800 parasites/µl, and the maximum parasitaemia recorded in group 5 was 81,633 parasites/µl. Applicable/inapplicable count corresponds to the number of samples. Logistic regression was performed to investigate the relationship between parasitaemia of the infection and applicability of the sample for WGS. OR (odds ratio), CI (confidence interval) and pI-value (p) are given