Table 2.

Anticoagulant therapy [4, 11, 13]

LMWH	Therapeutic dose	Monitoring
Nadroparin  0 – 2 m Enoxaparin  0 – 2 m Dalteparin  0 – 2 m Tinzaparin  0 – 2 m	120-150 U/kg/12 h sc 1,7 mg/kg/12 h sc in preterm neonates 1,5 mg/kg/12 h sc in term neonates 150 U/kg/12 h sc 275 U/kg/24 h sc	Check anti-FXa level 4 h after 2nd dose; Target anti-FXa level: 0.5–1.0 U/mL Check platelets regularly

Abbreviations: LMWH low-moleculair-weight heparin, h hour, m months, sc subcutaneously