Table 4.
Pattern of deletion of pfhrp2, pfhrp3 and their flanking genes in RDT false negatives
| Pfhrp2 exon 2, PF3D7_0831800 | Pfhrp2 exon 1–2, PFD7_0831800 | PFD7_0831900 (MAL7P1.230) | PFD7_0831700 (MAL7P1.228) | Pfhrp3 exon 1–2, PF3D7_1372200 | PF3D7_1372400 (MAL13P1.475) | PF3D7_1372100 (MAL13P1.485) | Study population | Frequency (%) |
|---|---|---|---|---|---|---|---|---|
| + | + | + | − | − | − | − | HIV negative | 1/8 (12.5) |
| + | + | − | − | − | − | − | HIV negative | 1/8 (12.5) |
| − | − | + | − | − | − | − | HIV negative | 1/8 (12.5) |
| − | − | − | − | − | − | − | Both HIV negative and positive | 5/8 (62.5) |
| + | + | + | + | + | + | + | Positive control | – |
| − | − | − | − | − | − | − | Negative control | – |