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. 2018 Feb 23;10:25. doi: 10.1186/s13148-018-0457-4

Table 3.

Top 20 gene ontology (GO) terms (BP = biological process) analysed for the 1000 top-ranked CP-associated DMPs

GO ID GO term Ontology No. of genes DM genes Unadjusted p value
GO:0098609 Cell-cell adhesion BP 1091 90 8.27E-06
GO:0007156 Homophilic cell adhesion via plasma membrane adhesion molecules BP 149 25 1.70E-05
GO:0042098 T cell proliferation BP 157 18 2.91E-05
GO:0042129 Regulation of T cell proliferation BP 133 16 3.28E-05
GO:0046649 Lymphocyte activation BP 557 46 6.47E-05
GO:0032729 Positive regulation of interferon-gamma production BP 58 10 7.55E-05
GO:0070661 Leukocyte proliferation BP 241 23 9.24E-05
GO:0001775 Cell activation BP 811 61 9.70E-05
GO:0050863 Regulation of T cell activation BP 270 26 1.27E-04
GO:0022610 Biological adhesion BP 1611 117 1.28E-04
GO:1903037 Regulation of leukocyte cell-cell adhesion BP 284 27 1.30E-04
GO:0070663 Regulation of leukocyte proliferation BP 187 19 1.66E-04
GO:0045321 Leukocyte activation BP 656 50 1.93E-04
GO:0007159 Leukocyte cell-cell adhesion BP 442 37 2.27E-04
GO:0098742 Cell-cell adhesion via plasma-membrane adhesion molecules BP 214 27 2.32E-04
GO:0050865 Regulation of cell activation BP 437 37 2.37E-04
GO:0016337 Single organismal cell-cell adhesion BP 669 54 2.49E-04
GO:0032649 Regulation of interferon-gamma production BP 85 11 2.51E-04
GO:0007155 Cell adhesion BP 1606 115 2.56E-04
GO:0045601 Regulation of endothelial cell differentiation BP 28 7 2.75E-04

DM differentially methylated, FDR false discovery rate