Table 5.

Gene ontology (GO) analysis for cerebral palsy-associated DMRs. (DM: differentially methylated; FDR: false discovery rate)

GO ID	GO term	Ontology	No. of genes	DM genes	Unadjusted p value	FDR
GO:0002705	Positive regulation of leukocyte mediated immunity	BP	80	5	4.57E-10	9.60E-06
GO:0002703	Regulation of leukocyte mediated immunity	BP	139	5	7.48E-09	5.26E-05
GO:0002699	Positive regulation of immune effector process	BP	142	5	7.52E-09	5.26E-05
GO:0050715	Positive regulation of cytokine secretion	BP	91	4	8.69E-08	4.56E-04
GO:0002443	Leukocyte mediated immunity	BP	258	5	1.42E-07	5.95E-04
GO:0002697	Regulation of immune effector process	BP	291	5	4.04E-07	1.09E-03
GO:0042742	Defence response to bacterium	BP	204	4	4.13E-07	1.09E-03
GO:0050778	Positive regulation of immune response	BP	571	6	4.17E-07	1.09E-03
GO:0050707	Regulation of cytokine secretion	BP	135	4	5.96E-07	1.39E-03
GO:0050663	Cytokine secretion	BP	154	4	9.84E-07	2.06E-03
GO:0001819	Positive regulation of cytokine production	BP	360	5	1.32E-06	2.52E-03
GO:0002876	Positive regulation of chronic inflammatory Response to antigenic stimulus	BP	2	2	1.61E-06	2.81E-03
GO:0050776	Regulation of immune response	BP	769	6	1.82E-06	2.82E-03
GO:0002682	Regulation of immune system process	BP	1191	7	1.88E-06	2.82E-03
GO:0002874	Regulation of chronic inflammatory response to antigenic stimulus	BP	3	2	2.15E-06	3.00E-03
GO:0050830	Defence response to Gram-positive bacterium	BP	68	3	2.45E-06	3.22E-03
GO:0002925	Positive regulation of humoral immune response mediated by circulating immunoglobulin	BP	4	2	2.82E-06	3.48E-03
GO:0002678	Positive regulation of chronic inflammatory response	BP	4	2	3.23E-06	3.76E-03
GO:0002718	Regulation of cytokine production involved in immune response	BP	52	3	3.84E-06	4.24E-03
GO:0002684	Positive regulation of immune system process	BP	820	6	4.24E-06	4.44E-03