Table 1.
Baseline clinical characteristics of the study subjects
| CeAD cases
|
Non-CeAD ischemic stroke |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| GWAS
|
Follow-up studies |
||||||||
| CADISP-1 | CADISP-2 | ||||||||
| n | 942 | 659 | 583 | ||||||
| Mean age (s.d.) | 44.2 | (10.0) | 44.6 | (10.5) | 43.6 | (9.4) | 44.6 | (10.5) | |
| Men, n (%) | 544 | (57.7) | 264 | (58.5) | 387 | (58.7) | 257 | (61.2) | |
| Location | Carotida, n (%) | 603 | (64.0) | 253 | (60.7)b | 375 | (56.9) | – | |
| Vertebral, n (%) | 305 | (32.4) | 147 | (35.3)b | 256 | (38.8) | – | ||
| Both, n (%) | 33 | (3.5) | 17 | (4.0)b | 26 | (3.9) | – | ||
| Clinical presentation | Cerebral ischemiac, n (%) | 729 | (77.4) | 333 | (79.5)b | 544 | (82.5) | – | |
| Ischemic stroke, n (%) | 606 | (64.3) | 281 | (67.1)b | 508 | (77.1) | – | ||
CeAD, cervical artery dissection.
a
Internal carotid artery dissection (one additional case had a common carotid artery dissection in CADISP-1).
b
Information on dissection site and associated ischemia was missing for 34 and 32 cases, respectively, in CADISP-2.
c
Cerebral ischemia corresponds to ischemic stroke or transient ischemic attack (including transient monocular blindness).