Table 6. Effects of the aqueous leaf extract of P. suberosa on lipid profile parameters, ALT, AST levels, and organ weights of mice after chronic treatment.
The data are shown as the means ± SEM (n = 9). The control group was given distilled water, and the treated group was given 50 mg/kg of the aqueous leaf extract.
| Parameters | Control | Treatment |
|---|---|---|
| Lipid profile parameters | ||
| Total Cholesterol (mg/dL) | 194.67 ± 0.82 | 161.11 ± 2.49** |
| Triglycerides (mg/dL) | 74.54 ± 6.63 | 65.50 ± 4.41* |
| HDL-CH (mg/dL) | 34.84 ± 1.14 | 34.12 ± 0.97 |
| LDL-CH (mg/dL) | 15.74 ± 0.65 | 14.73 ± 0.53 |
| ALT & AST levels | ||
| ALT (IU/L) | 21.31 ± 0.36 | 21.79 ± 0.23 |
| AST (IU/L) | 12.67 ± 0.24 | 12.77 ± 0.61 |
| Organ weights | ||
| Liver (g) | 1.8682 ± 0.0689 | 1.8440 ± 0.0101 |
| Spleen (g) | 0.1430 ± 0.0547 | 0.1552 ± 0.0829 |
| Kidney (g) | 0.7146 ± 0.2001 | 0.6365 ± 0.0438 |
| Testes (g) | 0.6064 ± 0.0120 | 0.6076 ± 0.0106 |
Notes.
*
Values are statistically significant at ∗p < 0.05.
- HDL-CH
- High-density lipoprotein cholesterol
- LDL-CH
- Low-density lipoprotein cholesterol
- ALT
- Alanine aminotransferase levels
- AST
- Serum aspartate aminotransferase