Table 8.
Groups | Orthokeratosis (%) | Drug activity (%) | Reduction in epidermal thickness (%) |
---|---|---|---|
Control (normal tail) | 11.20±2.10 | – | – |
Plain gel | 12.31±2.37 | 1.25 | 9.25±2.09 |
Zarotex gel (0.1%; commercial product) | 34.13±3.76* | 25.82 | 22.64±3.08 |
Act gel | 41.42±3.46* | 34.03 | 59.49±3.48 |
Act niosomal gel | 68.51±3.22*,** | 64.54 | 73.60±2.32** |
Notes: Each value represents the mean ± SE (n=6).
p<0.05 vs control;
p<0.05 Act niosomal gel vs other gel formulations.
Abbreviation: Act, Acitretin.