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. 2018 Feb 23;8:3549. doi: 10.1038/s41598-018-21552-1

Figure 4.

Figure 4

Allopurinol-treated ankle sprain patients are partially protected against unloading-induced skeletal muscle atrophy. (A) Quantification of the changes in soleus muscle volume during lower leg immobilization with a posterior ankle splint. (B) Quantification of the changes in soleus muscle CSA during lower leg immobilization with a posterior ankle splint. (C) Representative volume images after analysis and segmentation of the soleus muscle in control and allopurinol-treated subjects. R = right, L = left, A = anterior, P = posterior, T = top, B = bottom. (D) Representative magnetic resonance images of control and allopurinol-treated subjects. The soleus muscle is shown in yellow.