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. 2018 Feb 12;128(3):1043–1056. doi: 10.1172/JCI94996

Figure 3. Effects of IKr blockade on severely and mildly affected patient iPSC-CMs.

Figure 3

(A and B) The effects of E-4031 (hERG channel blocker) at 2 different concentrations on the IV-17, III-3, and IV-15 trio as well as the IV-17, IV-3, and IV-4 trio. Between 8 and 32 cells were analyzed per E-4031 treatment condition for APD in A and B. NT, no treatment. *Statistical significance (P < 0.05) as determined by ANOVA in A and B.