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. 2018 Feb 12;128(3):1043–1056. doi: 10.1172/JCI94996

Figure 4. L-type calcium current density increase revealed by patient-specific iPSC-CMs.

Figure 4

(A) Representative macroscopic whole-cell L-type Ca2+ (ICaL) traces from the IV-17, III-3, and IV-15 paired trio. (B) ICaL from the IV-17, IV-3, and IV-4 paired trio. (C) Summary data from A and B. Between 24 and 95 cells from 9 different iPSC clones (3 each from IV-17, III-3, IV-15 paired trio) were analyzed in A. Between 20 and 47 cells from 9 different iPSC clones (3 each from IV-17, IV-3, IV-4 paired trio) were analyzed in B. *Statistical significance (P < 0.05) as determined by ANOVA in C.