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. 2018 Feb 19;128(3):1178–1189. doi: 10.1172/JCI97702

Figure 7. Improved lipid metabolism in HFD Lrp1-βKO islets.

Figure 7

Experiments used pancreatic islets from mice 8 months after doxycycline treatment. (A–D) RT-qPCR of lipid metabolism genes in the HFD groups. n = 3 to 4 mice per genotype. Data are presented as mean ± SEM. *P < 0.05; **P < 0.01 for Lrp1-βKO versus control by 2-tailed unpaired Student’s t test. (E–G) Representative Western blots (E) and quantitation (F and G) of both PPARγ isoforms. n = 2 mice per condition. Data are presented as mean ± SEM.