Table 1.
Current adjuvant clinical trials in uveal melanoma.
| Mechanism | Trial | Phase | Identifier | Status |
|---|---|---|---|---|
| Chemotherapy | Dacarbazine + interferon-alfa | II | NCT01100528 | Accrual complete |
| Cisplatin, tamoxifen + sunitinib | II | NCT00489944 | Unknown | |
| Fotemustine versus observation | III | EudraCT Number 2008-005691-27 | Accrual complete | |
| Targeted therapy | Crizotinib | II | NCT02223819 | Recruiting |
| Sunitinib versus valproic acid | II | NCT02068586 | Recruiting | |
| Immunotherapy | Ipilimumab + nivolumab | II | NCT01585194 | Recruiting |
| Dendritic cell vaccine | I/II | NCT00929019 | Recruiting | |
| Liver-directed therapy | Prophylactic liver RT | II | NCT02336763 | Terminated* |
*
Study terminated due to lack of accrual.