Table 3. Location of folate metabolism-related genes on potato chromosomes and closest significant SNPs.
| Folate gene | Chromosome | Closest SNPs (SSTA, STA, or both) |
Distance from folate gene (Mb) |
|---|---|---|---|
| DHFR | Chr. 1 | solcap_snp_c2_49910 (SSTA) | <0.1 |
| DHNTP-PPase | Chr. 3 | solcap_snp_c2_50637 (SSTA) | <0.6 |
| 5-FCL | Chr. 3 | solcap_snp_c1_5799 (SSTA) | <0.0 |
| DHNA | Chr. 4 | solcap_snp_c2_21636 (SSTA) solcap_snp_c2_21934 (both) |
<2.6 <6.8 |
| ADCS | Chr. 4 | solcap_snp_c2_21636 (SSTA) | <17 |
| HPPK/DHPS | Chr. 5 | solcap_snp_c2_55452 (SSTA) | <6.3 |
| FPGS | Chr. 5 | solcap_snp_c2_10287 (SSTA) | <0.1 |
| GCHI | Chr. 6 | solcap_snp_c2_9233 (SSTA) solcap_snp_c2_5858 (STA) solcap_snp_c1_13135 (both) |
<0.7 <7.4 <6.8 |
| DHFS | Chr. 6 | solcap_snp_c2_42355 (SSTA) solcap_snp_c2_48886 (both) |
<1.3 <3.1 |
| GGH1 | Chr. 7 | solcap_snp_c2_42761 (SSTA) | <0.3 |
| GGH3 | Chr. 7 | solcap_snp_c2_42761 (SSTA) | <0.3 |
| DHNA | Chr. 10 | solcap_snp_c2_51076 (SSTA) | <5.9 |
| GGH2 | Chr. 10 | solcap_snp_c1_329 (SSTA) | <2.0 |
| ADCL | Chr. 11 | solcap_snp_c2_34204 (SSTA) | <2.5 |
| UDP-Glu-pABA glucosyltransferase | Chr. 12 | solcap_snp_c2_5333 (SSTA) | <0.4 |
SNP, single nucleotide polymorphism; SSTA, survey SNP-trait association; STA, SNP-trait association; DHFR, dihydrofolate reductase; DHNTP-PPase, dihydroneopterin triphosphate diphosphatase; 5-FCL, 5-formyltetrahydrofolate cycloligase; DHNA, dihydroneopterin aldolase; ADCS, aminodeoxychorismate synthase; HPPK/DHPS, 6-hydroxymethyldihydropterin pyrophosphokinase/ dihydropteroate synthase; FPGS, folylpolyglutamate synthase; GCHI, GTP cyclohydrolase I; DHFS, dihydrofolate synthase; GGH, γ-glutamyl hydrolase; ADCL, aminoedoxychorismate lyase; UDP-Glu-pABA glucosyltransferase, UDP-glucose-p-aminobenzoate glucosyltransferase.