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. 2018 Feb 23;13(2):e0193380. doi: 10.1371/journal.pone.0193380

Fig 6. AZD9977 does not change urinary Na+/K+ ratio in rat urine electrolyte secretion model.

Fig 6

a) Salt deprived rats were treated with increasing doses of eplerenone (a) or AZD9977 (b), urine collection for 8 hours after dose. Average +/- SEM; n = 8; *p<0.05 compared to vehicle. c) Salt deprived rats were treated with 10 or 30 mg kg-1 eplerenone in absence or presence of 100 mg kg-1 AZD9977, urine collection for 8 hours after dose. Average +/- SEM; n = 8, *p<0.05 vs vehicle. #p<0.05 vs eplerenone treatment in absence of AZD9977.