Table 3.
Effects of PrEP Use and Adherence on Condomless Anal Sex in HIV-Negative Seroconcordant Partnerships
| Outcome | Predictor | IRR | Confidence Interval (95%) | p-value |
|---|---|---|---|---|
| Insertive sex | Participant on PrEP | 0.89 | 0.68 – 1.16 | 0.388 |
| Non-Adherent | 1.03 | 0.71 – 1.52 | 0.864 | |
| Adherent | 0.8 | 0.57 – 1.11 | 0.175 | |
|
| ||||
| Insertive CAS | Participant on PrEP | 1.16 | 0.79 – 1.71 | 0.451 |
| Non-Adherent | 1.53 | 0.89 – 2.63 | 0.122 | |
| Adherent | 0.94 | 0.59 – 1.51 | 0.807 | |
|
| ||||
| Receptive sex | Participant on PrEP | 1.27 | 1 – 1.61 | 0.049 |
| Non-Adherent | 1.33 | 0.95 – 1.88 | 0.101 | |
| Adherent | 1.24 | 0.94 – 1.62 | 0.129 | |
|
| ||||
| Receptive CAS | Participant on PrEP | 1.49 | 1.05 – 2.12 | 0.025 |
| Non-Adherent | 1.79 | 1.09 – 2.93 | 0.021 | |
| Adherent | 1.33 | 0.88 – 2.01 | 0.177 | |
|
| ||||
| Total anal sex | Participant on PrEP | 1.07 | 0.9 – 1.28 | 0.441 |
| Non-Adherent | 1.12 | 0.86 – 1.45 | 0.392 | |
| Adherent | 1.04 | 0.85 – 1.29 | 0.683 | |
|
| ||||
| Total CAS | Participant on PrEP | 1.32 | 1 – 1.76 | 0.052 |
| Non-Adherent | 1.62 | 1.09 – 2.42 | 0.018 | |
| Adherent | 1.16 | 0.83 – 1.62 | 0.399 | |
NOTE: HIV-negative seroconcordant refers to partnerships in which the participant is HIV-negative and the partner is perceived HIV-negative/unknown. PrEP = pre-exposure prophylaxis; IRR = incidence-rate ratio; CAS = condomless anal sex.