Fig. 5.

Fat necrosis. A 48-year-old woman with prior bilateral prophylactic mastectomies and implant reconstruction presented with a palpable abnormality on the inner aspect of the right breast. a Mammography showed new grouping of pleomorphic-appearing calcifications with associated irregular mass in the upper outer quadrant of the left breast (red arrow). b Ultrasound showed a heterogeneous, complex, cystic and solid oval mass with no vascularity. c Post-contrast axial MRI showed mild peripheral enhancement with central, non-enhancing fat consistent with benign fat necrosis (red arrow). d Histological photomicrograph (original magnification ×10, haematoxylin-eosin) showed calcification (blue star), vacuolisation and saponification of the remnants of the necrotic fat (red arrow), epithelioid macrophages and lymphocytes (yellow arrow). Normal fat is also visualised (green arrow)