Table 3.
Mean percentage difference (95% confidence intervals) in adipokines at age 60–64 by accumulation of leisure-time physical activity (LTPA) across adulthood.
| Leptin (ng/ml) |
Adiponectin (ug/ml) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Men (n = 724) | p | Women (n = 783) | p -value | Men (n = 723) | p | Women (n = 783) | p -value | |
| Adulthood LTPA score (0–8): per 1-unit increase | ||||||||
| Model 1 | −3.9 (−6.3, −1.6) | 0.001 | −7.8 (−10.1, −5.5) | <0.001 | −0.6 (−2.7, 1.5) | 0.5 | 4.2 (2.4, 6.0) | <0.001 |
| Model 2 | −4.4 (−6.2, −2.6) | <0.001 | −2.4 (−4.2, −0.6) | 0.01 | −0.8 (−3.0, 1.3) | 0.4 | 2.1 (0.3, 3.9) | 0.02 |
| Model 3 | −4.2 (−6.0, −2.4) | <0.001 | −2.4 (−4.2, −0.5) | 0.01 | −1.1 (−3.2, 1.1) | 0.3 | 2.0 (0.2, 3.8) | 0.03 |
Model 1: adjusted for age. Model 2 also adjusted for body mass index, smoking history and socioeconomic position. Model 3: as for model 2 plus adjustment for hypertension, diabetes, stroke, angina, myocardial infarction. Evidence of deviation from linearity was found between the adult LTPA score and leptin in men (p = 0.009).