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. 2018 Jan 1;145(1):dev153544. doi: 10.1242/dev.153544

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© 2018. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — GFAP-YFP-expressing cells in the DG and population-level dynamics of hippocampal neural stem cells. (A,C) GFAP-YFP-positive cells in 8-week-old (A) and 56-week-old (C) GFAP-YFP reporter mice. Scale bars: 100 μm. (B,D) Representative confocal images of immunostaining for GFP (green) and S100β (red). Shown are examples of a GFAP⁺/S100β⁻ neural stem cell (B) and a GFAP⁺/S100β⁺ astrocyte (D). Scale bars: 20 μm. (E,F) Fit of the proposed model to the total number of NSCs (E) and the fraction of BrdU-incorporating NSCs (F). Estimated parameters are displayed in Table 1.