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. 2018 Feb 19;9:72. doi: 10.3389/fneur.2018.00072

Table 5.

Means and SEMs of participant group scores on symptom self-report questionnaires and cognitive instruments.

Participant group DC-N (n = 17) DC-HP (n = 3) mTBI-N (n = 27) mTBI-HP (n = 12) mTBI main effect HP Main
Self-report Questionnaires
CAPS posttraumatic stress disorder (PTSD) Diagnosis 2/17 11.8% 1/3 33.3% 14/27 51.9% 9/12 75.0% p < 0.005 p < 0.05
CAPS Total Score 53.3 ± 6.1 65.0 ± 9.4 p = 0.291
PTSD CheckList-Military 26.1 ± 3.2 35.0 ± 9.0 46.2 ± 3.1 54.0 ± 5.7 p < 0.0001 p < 0.02
Neurobehavioral Symptom Inventory 8.4 ± 2.6 11.3 ± 5.7 26.9 ± 3.2 37.1 ± 6.6 p < 0.0001 p < 0.02
Patient Health Questionnaire-9 3.9 ± 1.3 6.7 ± 3.3 9.7 ± 1.4 12.7 ± 2.9 p < 0.005 p = 0.076
Pittsburgh Sleep Quality Index 5.8 ± 1.0 7.0 ± 3.5 10.4 ± 1.1 11.1 ± 1.7 p < 0.005 p = 0.308
AUDIT-C 2.7 ± 0.4 3.0 ± 1.0 4.1 ± 0.4 4.2 ± 0.9 p < 0.05 p = 0.369
Cognitive measures
Trail making test trails A 55.0 ± 2.5 69.0 ± 4.0 55.6 ± 2.0 54.4 ± 3.4 p = 0.665 p = 0.700
Trail making test trails B 52.7 ± 3.2 63.0 ± 4.0 48.1 ± 2.8 47.8 ± 3.3 p = 0.128 p = 1.000
Ruff 2 & 7—total speed 50.1 ± 2.3 59.5 ± 1.5 50.6 ± 1.7 46.5 ± 2.3 p = 0.462 p = 0.496
Ruff 2 & 7—total accuracy 47.1 ± 2.2 51.0 ± 4.0 45.8 ± 2.1 46.3 ± 2.9 p = 0.742 p = 0.731

Higher scores on symptom self-report questionnaires reflect endorsement of more severe and/or frequent symptoms. Higher scores on the cognitive tests indicate better performance. The fractions in the “CAPS PTSD Diagnosis” row of the table indicate the number of participants with a clinical diagnosis of PTSD in each group divided by the total number of participants in the group. The two columns to the far right indicate the level of significance of the main effects of mild traumatic brain injury (mTBI Main) and hypopituitarism (HP Main) on group scores on each instrument by two-way analysis of variance. One mTBI-N and one mTBI-HP participant scored below the cutoff level on the Test of Memory Malingering, and their scores have been deleted from the statistical computations for cognitive measures. Probability values < 0.02 are printed in red to indicate statistical significance of main effects.

CAPS, Clinician-Administered PTSD Scale for DSM-IV; AUDIT-C, alcohol use disorders identification test-consumption.