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. 2017 Feb 1;63(2):E58–E67.

Table V.

Associations among clinical outcomes, cagA, and the i-region genotype of vacA.

(A) GC

vacA Total

s1/i1/m1 s1/i1/m2 s1/i2/m2 s1/i3/m2 s2/i2/m2 s2/i2/m2-m1b Negative
cagA East Asian 29 2 0 0 0 0 1 32
Western 2 0 0 0 0 0 0 2
Negative 0 0 0 0 0 0 0 0
Total 31 2 0 0 0 0 1 34
(B) GU

vacA Total

s1/i1/m1 s1/i1/m2 s1/i2/m2 s1/i3/m2 s2/i2/m2 s2/i2/m2-m1b Negative
cagA East Asian 16 0 0 0 0 0 0 16
Western 0 0 0 0 0 0 0 0
Negative 0 0 0 0 0 0 0 0
Total 16 0 0 0 0 0 0 16
(C) DU

vacA Total

s1/i1/m1 s1/i1/m2 s1/i2/m2 s1/i3/m2 s2/i2/m2 s2/i2/m2-m1b Negative
cagA East Asian 13 1 1 0 0 0 0 15
Western 2 1 6 1 0 0 0 10
Negative 0 0 0 0 1 0 0 1
Total 15 2 7 1 1 0 0 26
(D) CG

vacA Total

s1/i1/m1 s1/i1/m2 s1/i2/m2 s1/i3/m2 s2/i2/m2 s2/i2/m2-m1b Negative
cagA East Asian 39 2 0 0 0 0 1 42
Western 2 0 3 1 2 0 0 8
Negative 2 0 0 0 4 1 0 7
Total 43 2 3 1 6 1 1 57

For the 133 H. pylori strains in which it was possible to type cagA, the numbers of H. pylori strains that exhibited each vacA genotype in various diseases are shown. GC: gastric cancer; GU: gastric ulcers; DU: duodenal ulcers; CG: chronic gastritis