TABLE 1.

Cystatin treatment regimens to combat NDM-1 K. pneumoniae pneumonia

Treatment	Dose (each) per mouse (pg)	Route	Time(s) of administration		% increased survival of mice infected with K. pneumoniae at the LD90
			Preinfection	Postinfection
rCST9 or rCSTC	50	i.n.	1 h		10 and 20, respectively
	500	i.n.	1 h		10
	50	i.n.		3 days	10
	500	i.n.		1 h and 3 days	10
	50	i.p. then i.p.		1 h and 3 days	5
rCST9 and rCSTC	50, 500	i.n. then i.p.		1 and 3 days	20
	500	i.p. then i.n.		1 and 3 days	10
	500	i.p.		4 days	5
	500	i.p.		5 days	0
	500	i.p.		1 and 3 days	5
	50, 500	i.n. then i.p.		1 and 3 days	25
	50, 500	i.n. then i.p.		1 h and 3 days	38
	500	i.p.		3 days	35