TABLE 4.
Name, indication, and therapeutic concentration in plasma of different sulfa antibacterial drugsa
| Name of sulfa antibacterial drug | Route of administration and indication | Therapeutic concn in plasmab |
|---|---|---|
| 4,Amino phenyl sulfone (dapsone) | Oral treatment for leprosy and Pneumocystis pneumonia | 0.63–1.66 |
| Sulfadiazine | Oral treatment of UTI | 19–40 |
| Sulfamethazine | Potential treatment of Escherichia coli enteritis in veterinary medicine | 64.0–88.4 |
| Sulfamethoxazole | Oral treatment for UTI and prostatitis | 15–65 |
| Sulfanilamide | Topical treatment of vaginal yeast infections | NA |
| Sulfacetamide | Topical treatment of acne and eye infections | NA |
| Sulfabenzamide | Topical intravaginal antibacterial preparation | NA |
| Sulfadoxine | Oral treatment used in combination with pyrimethamine to treat or prevent malaria | 130–200 |
| Sulfanitran | Veterinary use, as an aid in the prevention of coccidiosis | NA |
| Sulfamerazine | In some countries, this medicine may be approved only for veterinary use, for example, in control of acute fowl cholera | NA |
| Sulfamonomethoxine | Used in veterinary medicine for the treatment of toxoplasmosis | NA |
| Sulfadimethoxine | Oral treatment of respiratory, urinary tract, enteric, and soft tissue infections | 120–180 |
| Succinylsulfathiazole | Treatment of intestinal amebiasis | 5% of a dose is absorbed after oral dose |
| Sulfathiazole | Oral and topical antimicrobial | NA |
| Sulfaguanidine | Treatment of bacillary dysentery | 15–40 |
| Sulfapyridine | Help in control of dermatitis herpetiformis (Duhring's disease) | 35–60 |
| Sulfametopyrazine (sulfalene) | Treatment of UTI and chronic bronchitis | 25–33 |
| Sulfametoxydiazine (sulfameter) | Long-acting sulfonamide antibacterial used as a leprostatic agent | 62–90 |
| Sulfisomidine | Treatment of pertussis | NA |
| Sulfisoxazole (sulfafurazole) | Treatment of bladder infections, ear infections, or meningitis | 127–210 |
| Sulfamethoxypyridazine | Treatment of vaginal irritation, severe acute thrush, and dermatitis herpetiformis, where it is an alternative therapy to dapsone | 110–180 |
a
UTI, urinary tract infection; NA, not available.
b
Values are in micrograms per milliliter unless otherwise indicated. Data are from reference 55.