TABLE 4.

Median values for urine pharmacokinetic parameters for vaborbactam, stratified by group

Renal study group	Median value for vaborbactam in urine (range)
	Amt excreted over 48 h (mg)	% of dose excreted over 48 h	Renal clearance (liters/h)
Normal (n = 8)	990 (760–1,140)	99.0 (76.0–114)	10.5 (6.64–14.5)
Mild (n = 8)	856 (642–1,000)	85.6 (64.2–100)	7.07 (4.34–10.3)
Moderate (n = 8)	845 (758–975)	84.5 (75.8–97.5)	5.21 (2.04–5.97)
Severe (n = 8)	743 (372–941)	74.3 (37.2–94.1)	0.978 (0.543–1.98)