TABLE 6.
PCR corrected efficacy of artemether-lumefantrine for each Plasmodium species observed in the PP populationa
| Parameter |
P. falciparum |
P. malariae |
P. ovale curtisi |
P. ovale wallikeri |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total no. of patients | No. of patients with ACPR (%) | 95% CI | Total no. of patients | No. of patients with ACPR (%) | 95% CI | Total no. of patients | No. of patients with ACPR (%) | 95% CI | Total no. of patients | No. of patients with ACPR (%) | 95% CI | |
| ACPR28 | 50 | 49 (98.0) | 94.0–100 | 27 | 27 (100) | 87.2–100* | 16 | 16 (100) | 79.4–100* | 11 | 10 (90.9) | 70.7–100 |
| ACPR42 | 44 | 42 (95.5) | 89.0–100 | 22 | 22 (100) | 84.6–100* | 14 | 14 (100) | 76.8–100* | 11 | 10 (90.9) | 70.7–100 |
In this table, the efficacy of artemether-lumefantrine is depicted for each infecting species allowing for multiple counting of single patients: e.g., in the “P. malariae” column, all P. malariae cases that occurred either as monoinfection or as mixed infection are considered. Every malaria event is split up into its causative species and likewise counted for each of these Plasmodium species. For example, a coinfection with P. falciparum and P. malariae is depicted both in the P. falciparum group and in the P. malariae group. This applies similarly to all other depicted groups. *, exact confidence interval computed with R binom package.