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(A) Deterministic simulation of population average ELF concentration-versus-time profile of formed colistin following pulmonary nebulization (I.T.) of CMS at 30 and 60 mg CBA twice daily in critically ill patients. Deterministic simulation of bacterial growth in the lungs following exposure to aerosolized CMS at 30 and 60 mg CBA twice daily in critically ill patients for P. aeruginosa ATCC 27853 (B), PAO1 (C), and FADDI-PA022 (D).
