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. 2018 Feb 20;5:31. doi: 10.3389/fmed.2018.00031

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Copyright © 2018 Shatil, Uddin, Matsuda and Figley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plots of T₂-relaxation time vs. formalin fixation time are shown for eight structures (genu of corpus callosum, splenium of corpus callosum, internal capsule, optic radiation, caudate nucleus, globus pallidus, putamen, and thalamus). The x-axis shows the time in hours, where x = 0 is the time of first formalin immersion. The y-axis shows the T₂ values in each structure. The lines with red and blue error bars (95% CIs) represent measurements from Subject 1 and Subject 2, respectively. Plots show T₂ changes in each structure throughout the fixation. An example T₂ map from Subject 2 has been shown in the top left.