Table 1.
Composition of Glimepiride transdermal patches
| Formulation code | Polymeric blend | Ratio | Polymer weight (mg) |
Dibutyl phthalate (% w/w) |
Chloroform: methanol (9:1 v/v) (mL) |
|---|---|---|---|---|---|
| G1 | ERL–ERS | 9:1 | 350 | 30 | 5 |
| G2 | ERL–ERS | 8:2 | 350 | 30 | 5 |
| G3 | ERL–ERS | 7:3 | 350 | 30 | 5 |
| G4 | ERL–ERS | 6:4 | 350 | 30 | 5 |
| G5 | ERL–ERS | 5:5 | 350 | 30 | 5 |
| G6 | ERL–ERS | 4:6 | 350 | 30 | 5 |
| G7 | ERL–ERS | 3:7 | 350 | 30 | 5 |
| G8 | ERL–ERS | 2:8 | 350 | 30 | 5 |
| G9 | ERL–ERS | 1:9 | 350 | 30 | 5 |
Abbreviations: ERK, Eudragit® (Ammonio Methacrylate Copolymer Ph Eur) RL 100; ERS, Eudragit® (Ammonio Methacrylate Copolymer Ph Eur) RS 100.