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. 2018 Feb 20;12:84. doi: 10.3389/fnins.2018.00084

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Copyright © 2018 Diotel, Charlier, Lefebvre d'Hellencourt, Couret, Trudeau, Nicolau, Meilhac, Kah and Pellegrini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biosynthetic pathways of neurosteroid synthesis. Cyp11a1, cytochrome P450 family 11 subfamily A member 1 (P450scc), cytochrome P450 side-chain cleavage; Cyp17, cytochrome P450 17α-hydroxylase/C17, 20-lyase; Aro, aromatase; 3β-HSD, 3β-hydroxysteroid dehydrogenase D5–D4 isomerase; 5α-R, 5α-reductase; 17β-HSD, 17β-hydroxysteroid dehydrogenase; Cyp21, cytochrome P450 21 hydroxylase; Cyp11, cytochrome P450 11β-hydroxylase B1 and/or B2. StAR, steroidogenic acute regulatory protein.