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. 2018 Feb 20;9:121. doi: 10.3389/fphar.2018.00121

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Copyright © 2018 Brymer, Fenton, Kalynchuk and Caruncho.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of CORT and etanercept on FST behavior. (A) Shows the effect of treatment on time spent immobile. The CORT rats spent significantly more time immobile than did the vehicle, CORT + etanercept, and etanercept rats (p < 0.05). (B) Shows the effect of treatment on time spent struggling. The CORT rats spent significantly less time struggling compared to the vehicle, CORT + etanercept, and etanercept rats (p < 0.05). (C) Shows the effect of treatment on time spent swimming. The CORT rats spent significantly less time swimming than did the vehicle, CORT + etanercept, and etanercept rats (p < 0.05). All data are represented as means ± standard error of the mean.