Table 1.

The screened SNV panel in Set A (father only), Set B (shared), and Set C (son only)

Set	CHR	Gene	SIFT	PPH2	Condel	Label	Mutation
Set A	12	SH2B3	0.01	0.887	0.436286	N	P242S
	5	MAP3K1	0.36	0.915	0.462039	N	D806N
	13	PARP4	0.32	0.002	0.52522	D	A1656P
	9	PTCH1	0.22	0.444	0.539701	D	P1315L
	2	UGT1A1	0.07	0.745	0.477712	N	G71R
	4	TET2	0.01	0.867	0.425092	N	P29R
	4	KDR	0.35	0.011	0.54766	D	Q472H
Set B	2	BARD1	0.77	0.015	0.525271	D	R378S
	17	TP53	0.17	0.372	0.541323	D	P72R
	13	CUL4A	0.16	0.054	0.546327	D	K644R
	12	PIK3C2G	0.04	0.985	0.612421	D	P952L
	1	PARP1	0.05	0.783	0.421476	N	K940R
	1	PARP1	0.24	0.731	0.385322	N	V762A
	2	ALK	0.38	0.003	0.545637	D	K1491R
	9	JAK2	0.05	0.027	0.552008	D	G127D
	13	PARP4	0.12	0.999	0.359572	N	A899T
	17	BRCA1	0.05		0.523632	D	S1634G
	17	BRCA1	0.04	0.065	0.632809	D	E1038G
	9	TSC1	0.44	0.015	0.53961	D	Q654E
Set C	17	TP53	0.17	0.372	0.541323	D	P72R
	16	FANCA	0.3	0.003	0.536669	D	T1328A
	3	BCL6	0.03	0.994	0.564365	D	A2T
	12	PIK3C2G	0.04	0.985	0.612421	D	P952L
	17	RNF43	0	0.902	0.447911	N	R117H
	5	FGFR4	0.04	0.803	0.52572	D	G388R
	13	FLT3	0.15	0.743	0.516309	N	T227M
	17	ERBB2	0.03	0.473	0.566675	D	P1170A
	20	PAK7		0	0.524865	D	R335P
	16	FANCA	0.11	0.349	0.598574	D	A412V
	5	NSD1		0.852	0.519655	N	S726P
	11	MEN1	0.06	0.02	0.597615	D	R300Q
	9	TSC1	0.44	0.015	0.53961	D	Q654E

Abbreviations: PPH2, PolyPhen-2; SIFT, Sorting Intolerant from Tolerant; SNV, single nucleotide variant; CHR, chromosome.