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. 2018 Feb 21;12:87. doi: 10.3389/fnins.2018.00087

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Copyright © 2018 Giger and Houart.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anterior neural plate patterning during gastrulation. In order to acquire eye identity, BMP signals have to be restricted anteriorly, and posteriorising Wnt ligands have to be antagonized by sFRPs and Dkk1. Blue: forebrain territory (telencephalon and eye field). Red: telencephalon; dark blue: eye field. Hh: Hedgehog; BMP: Bone Morphogenetic Protein; sFRPs: secreted Frizzled Receptor Proteins; Dkk1: Dickkopf 1.