Table 1.
Participant demographics, intensity, and blissful state scores.
| Name | Age | 1st Session dose¤ | Intensity | Blissful state | 2nd Session dose¤ | Intensity | Blissful state | Reduction in heavy drinking days§ |
|---|---|---|---|---|---|---|---|---|
| Jason | 42 | 0.3 | 3.00 | 27.67 | – | – | – | 100% |
| Adam | 47 | 0.3u | 3.50 | 52.67 | 0.3u | 3.75 | 16.33 | 100% |
| Ashley | 41 | 0.3 | 2.25 | 78 | – | – | – | 9.21% |
| Charles | 30 | 0.3 | 2.25 | 13.67 | 0.4 | 2.50 | 4 | 19.43% |
| Zach | 25 | 0.3 | 2.75 | 44 | 0.4 | 1.75 | 14.33 | 72.26% |
| Keith | 40 | 0.3 | 1.75 | 12.33 | 0.4 | 1.25 | 3.67 | 42.84% |
| Lisa | 56 | 0.3 | 2.25 | 18 | – | – | – | X |
| Heather | 28 | 0.3 | 0.00 | 3.33 | 0.4 | 0.25 | 3.17 | 100% |
| David | 53 | 0.3 | 3.00 | 18 | 0.4 | 3.25 | 81.33 | 13.67% |
| Michelle | 39 | 0.3 | 3.50 | 36.67 | 0.4u | 3.00 | 92 | 100% |
Dosages reported are mg of pure psilocybin per kilo of the participant's weight. Actual dosages were compounded prior to the medication session based on current weight.
–Participant did not complete a second psilocybin session.
Indicates scores >0.6 on all MEQ subscales as rated after each session. If this criterion was met during the first session then psilocybin dosage was not increased for the second session.
Relative proportion of the number of heavy drinking days reported during weeks 9–12 of the study to the number of heavy drinking days at baseline. For instance, if a participant reported 30 drinking days at baseline and 6 during weeks 9–12, they have a reported a reduction of 80%. For full analysis of this and other outcomes see Bogenschutz et al. (2015).
1st session with dose of 0.3 mg/kg (N = 10) HRS Intensity score Mean 2.43 (SD 1.03) Blissful State Mean 30.4 (SD 22.7).
2nd Session with dose of 0.4 mg/kg (N = 6, underlined scores) HRS Intensity score mean 2.0 (SD 1.14) Blissful State Mean 33 (SD 41.8).
X—No data available.