Table 2.

Abundance values of transcripts showing significant variations (p-value < 0.03) between the ΔSCO4117 mutant and the S. coelicolor M145 wild-type strain quantified in MM solid cultures (44 h), and grouped into functional categories.

Function		SCO no°	Gene	Log2 fold-change (ΔSCO4117/Wt)	Fold-change (ΔSCO4117/Wt)
Secondary metabolism	Deoxysugar synthases	SCO0381	Glycosyl transferase	−5.2	0.03
		SCO0382	Dehydrogenase	−5.2	0.03
		SCO0383	Glycosyl transferase	−3.8	0.07
		SCO0386	Asparagine synthetase	−3.3	0.1
		SCO0387	Oxidoreductase	−3.1	0.1
		SCO0389	Lipoprotein	−3.8	0.07
	ACT	SCO5071	Dehydrogenase	−8	0.003
		SCO5072	Dehydrogenase	−4.5	0.04
		SCO5074	Dehydratase	−5.6	0.02
		SCO5077	actVA2	−3.3	0.1
		SCO5078	actVA3	−2.8	0.1
		SCO5085	actII-4	−4	0.06
		SCO5086	actIII	−5.7	0.02
		SCO5087	actIORF1	−3	0.1
		SCO5092	actVB	−3	0.1
Differentiation		SCO1541	ssgB	−3.4	0.09
		SCO2705	chpF	−5.1	0.03
		SCO2716	chpA	−3.8	0.07
		SCO2717	chpD	−3.8	0.07
		SCO2718	rdlA	−7.5	0.005
		SCO2719	rdlB	−5.5	0.02
		SCO4002	nepA	−4.5	0.04
		SCO7449	Spore pigmentationa	−2.6	0.2
Stress		SCO4684	scoF3	−4.5	0.05
Regulators		SCO0194	Sigma factor	2.4	5.2
Catabolic enzymes		SCO1236	Urease	2.7	6.5
Anabolic enzymes		SCO2162	Quinolinate synthetase	2.2	4.6
		SCO6102	Nitrite/sulphite reductase	2.5	5.7
Unknown		SCO4256	Hypothetical protein	2.2	4.6
		SCO1293	Putative acetyltransferase	2.3	4.9
		SCO4258	Putative hydrolytic protein	2.8	6.9
		SCO0195	Putative lipoprotein	2.9	7.5
		SCO2788	Hypothetical protein	2.9	7.5
		SCO7643	Hypothetical protein	∞b	∞b

The genes discussed in the text are indicated.

^aSecreted protein related to spore pigmentation (Salerno et al., 2013).

^bTranscripts not detected in the wild-type strain.