Table 3.
ANOVA results (three-way mixed ANOVA) for the control vs. patient comparison of gray matter outcomes.
| Between-subject | Within-subject | |||||
|---|---|---|---|---|---|---|
| Group | Group*ROI | Group*TP*ROI | ||||
| F-ratio (1, 18) | p-value | F-ratio (35, 630) | p-value | F-ratio (35, 630) | p-value | |
| GFA | 6.205 | 0.023* | 2.340 | <0.001* | 2.235 | <0.001* |
| PA | 6.256 | 0.022* | 2.218 | <0.001* | 1.669 | 0.010* |
| RTAP | 1.548 | 0.229 | 1.249 | 0.157 | 1.326 | 0.102 |
| RTPP | 2.064 | 0.168 | 2.152 | <0.001* | 1.843 | 0.003* |
| MSD | 2.681 | 0.119 | 2.601 | <0.001* | 0.552 | 0.990 |
| FA | 7.346 | 0.014* | 2.082 | <0.001* | 2.731 | <0.001* |
| MD | 0.186 | 0.671 | 1.825 | 0.003* | 1.105 | 0.314 |
The three independent variables were Group (between-subject factor), Time Point (TP) and Region (ROI) (within-subject factors), while the dependent variable was the mean index value. Group, along with Group*ROI and Group*TP*ROI interactions, are expressed in terms of F-ratio (degree of freedom, error) and p-values.
*
, significant values.