Table 2.
FIC indexes of the combined action of the Copaifera duckei Dwyer oleoresin or (–)-polyalthic acid and chlorhexidine against bacteria involved in dental carie and endodontic infections.
| Microorgranisms | MIC 1 (μg mL−1) | MIC 2 (μg mL−1) | FIC 1 (μg mL−1) | FIC 2 (μg mL−1) | FIC index | Interpretation | |
|---|---|---|---|---|---|---|---|
| Oleoresin × CDH | S. mutans (25175 ATCC) | 50 | 0.922 | 25 | 0.230 | 0.74 | Additivity |
| S. sobrinus (33478 ATCC) | 50 | 0.922 | 50 | 0.461 | 1.50 | Indifference | |
| L. casei (11578 ATCC) | 25 | 3.688 | 25 | 0.461 | 1.12 | Indifference | |
| L. casei (Clinical isolate) | 25 | 3.688 | 12.5 | 0.461 | 0.62 | Additivity | |
| P. gingivalis (33277 ATCC) | 6.25 | 1.844 | 12.5 | 1.844 | 3.00 | Indifference | |
| P. micros (Clinical isolate) | 25.0 | 7.375 | 6.25 | 14.75 | 2.25 | Indifference | |
| Polyalthic acid × CDH | S. mutans (25175 ATCC) | 50 | 0.922 | 50 | 0.230 | 1.24 | Indifference |
| S. sobrinus (33478 ATCC) | 12.5 | 0.922 | 12.5 | 0.922 | 2.00 | Indifference | |
| L. casei (11578 ATCC) | 25 | 7.375 | 25 | 0.922 | 1.25 | Indifference | |
| L. casei (Clinical isolate) | 25 | 7.375 | 25 | 0.461 | 1.12 | Indifference | |
| P. gingivalis (33277 ATCC) | 3.12 | 1.844 | 3.12 | 3.688 | 3.00 | Indifference | |
| P. micros (Clinical isolate) | 12.5 | 7.375 | 6.25 | 14.75 | 2.5 | Indifference | |
1. Oleoresin or (–)-polyalthic acid; 2. Chlorhexidine.