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. 2018 Feb 26;13(2):e0193438. doi: 10.1371/journal.pone.0193438

Fig 3. Psychosine content and GALC activity correlated with aging in mid-aged cohort.

Fig 3

Psychosine content (A,B) and GALC activity (C,D) in cortical brain tissue from a combined cohort of mid-aged neuropsychiatric patients and healthy control patient tissue was compared to age at time of death. Linear regression revealed a significant positive correlation between psychosine content in the white matter (A) and age in this cohort, but a similar positive correlation did not reach significance in grey matter (B). However, a significant negative correlation between GALC activity and age was present in both white (C) and grey (D) matter. (Statistical test of slope significantly non-zero, *p<0.05).